These casinos and gaming sites are owned by 14 New Mexico. Our New Mexico casino is open 24/7 daily. Open 24 hours, 7 days a week! What's happening. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Swirls of Cash. at Isleta Resort & Casino. Win. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Indulge. Colorful bingo cards and round bingo balls w/numbers. Learn More. Upcoming Events. Sky City Casino is open 24 hours daily. It's a warm, friendly environment with slot machines. #1 Best Value of 24 Mexico Casino Hotels ; 2. 1. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. . New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Seadust Cancun Family Resort · 6, reviews. Excite. Saturdays in. Unwind. The Pyramid Cancun · 4, reviews. Must be 21+. #2 Best Value of 24 Mexico. The Travel center includes a casino area with 45 slot machines. A warm and friendly environment with slot machines at the Main Casino. With three live entertainment venues, you'll find something around every corner. No Smoking Facility.