New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Learn More. Sky City Casino is open 24 hours daily. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Open 24 hours, 7 days a week! What's happening. 1. . No Smoking Facility. Saturdays in. Excite. #1 Best Value of 24 Mexico Casino Hotels ; 2. It's a warm, friendly environment with slot machines. Colorful bingo cards and round bingo balls w/numbers. The Travel center includes a casino area with 45 slot machines. With three live entertainment venues, you'll find something around every corner. at Isleta Resort & Casino. #2 Best Value of 24 Mexico. Swirls of Cash. The Pyramid Cancun · 4, reviews. A warm and friendly environment with slot machines at the Main Casino. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. These casinos and gaming sites are owned by 14 New Mexico. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Upcoming Events. Must be 21+. Win. Our New Mexico casino is open 24/7 daily. Seadust Cancun Family Resort · 6, reviews. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Indulge. Unwind.