Must be 21+. A warm and friendly environment with slot machines at the Main Casino. Win. With three live entertainment venues, you'll find something around every corner. Indulge. Upcoming Events. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Learn More. 1. Saturdays in. #1 Best Value of 24 Mexico Casino Hotels ; 2. #2 Best Value of 24 Mexico. Colorful bingo cards and round bingo balls w/numbers. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. The Pyramid Cancun · 4, reviews. Excite. These casinos and gaming sites are owned by 14 New Mexico. Seadust Cancun Family Resort · 6, reviews. Swirls of Cash. The Travel center includes a casino area with 45 slot machines. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. It's a warm, friendly environment with slot machines. Open 24 hours, 7 days a week! What's happening. No Smoking Facility. Unwind. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Sky City Casino is open 24 hours daily. Our New Mexico casino is open 24/7 daily. at Isleta Resort & Casino. . Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily.